Scars form when the skin’s normal healing process is disrupted, resulting in disorganized collagen fibres, a loss of elasticity, and sometimes a change in colour or texture. Microneedling With PRP Therapy in Riyadh For individuals exploring Microneedling With PRP Therapy in Riyadh, this combination treatment offers a way to remodel scar tissue by stimulating the body’s own regenerative mechanisms.
How the Combination Works on Scars
Microneedling, also known as collagen induction therapy, uses ultra-fine needles to create controlled micro-injuries in the skin. This triggers the body’s natural wound-healing cascade, breaking down old, disorganised collagen and stimulating the production of new, more organised collagen and elastin. When combined with platelet-rich plasma (PRP), the effect is amplified.
PRP is derived from a small sample of your own blood. After centrifugation, it contains a high concentration of growth factors that promote cell proliferation, angiogenesis (new blood vessel formation), and fibroblast activity—all of which support scar remodelling. Applied during microneedling, the PRP penetrates deeply through the microchannels, delivering these growth factors directly to the scar tissue .
Clinical Evidence: Superior Results Over Microneedling Alone
Post-Acne Scars
A 2025 clinical study of 65 patients with post-acne scars compared microneedling with PRP against microneedling with saline . The PRP group showed a 43% improvement in scar severity, compared to just 19% in the saline group. Patient satisfaction was also significantly higher—80% of PRP patients reported being very satisfied, versus 53% in the control group .
The split-face study further confirmed these findings, with the combination side showing a 55.29% reduction in quantitative scar scores, compared to 33.89% on the microneedling-only side . The combination group also demonstrated significantly higher rates of excellent response (37% vs 10%) .
Burn and Surgical Scars
A retrospective study of 107 patients with various scar types (including burn scars, surgical scars, and traumatic scars) found that 21.5% reported softer and more elastic scar tissue after just one treatment . Other improvements included better tissue mobility (7.5%), improved colour (7.5%), and a healthier overall skin appearance (5.6%) . No serious adverse effects were reported, confirming the treatment’s safety profile .
For cleft lip scars, a 2025 randomised trial found that microneedling with PRP offered superior scar reduction and patient satisfaction compared to microneedling with vitamin C serum .
Breast Reduction Scars
A 2026 prospective study on breast reduction scars found that both microneedling alone and microneedling with PRP were safe and effective for incisional scars across all skin types . However, no additional benefit was observed from adding PRP in this specific study, suggesting that results may vary depending on scar type and technique .
Safety and Side Effects
Across all studies, the treatment demonstrated a favourable safety profile. Transient erythema (redness) and edema (swelling) were the most common side effects, typically resolving within 4–5 days . No cases of hyperpigmentation or severe complications were reported in the major studies . Mild soreness during treatment was reported by 11.2% of patients, with only a small number describing it as mildly painful .
The treatment is suitable for various skin types, including Fitzpatrick skin type IV, which was the most common in one study . For those considering prp treatment in saudi arabia, this combination offers a safe and effective option for scar reduction.
For those seeking expert guidance and customised aesthetic care, you can book an appointment consultation at the Enfield Royal Clinic.
Frequently Asked Questions
How many sessions will I need for scar improvement?
Most clinical protocols recommend 3 sessions, spaced 4 weeks apart, for optimal scar remodelling and visible improvement .
When will I see results from the treatment?
Some improvement may be visible after the first session, but the most significant results develop over several months as new collagen remodels the scar tissue .
Is the treatment effective for old scars?
Yes, studies included scars ranging from 3 months to 70 years old, with patients reporting improvements in pliability, colour, and texture across all scar ages .
Does PRP plus microneedling work for all scar types?
The treatment has shown effectiveness for acne scars, burn scars, surgical scars, and traumatic scars . Results may vary by scar type and individual response.
What are the possible side effects of the treatment?
Common side effects include temporary redness and swelling that resolve within 4–5 days. No severe complications or hyperpigmentation were reported in the major studies .